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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...

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Related Experiment Video

Updated: Jul 6, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Environmental controls of allergies.

Berrylin J Ferguson1

  • 1Department of Otolaryngology, Division of Sinonasal Disorders and Allergy, University of Pittsburgh Medical Center, Suite 500, 200 Lothrop Street, Pittsburgh, PA 15213, USA. fergusonbj@upmc.edu <fergusonbj@upmc.edu>

Otolaryngologic Clinics of North America
|March 11, 2008
PubMed
Summary

Environmental controls are key for managing allergic rhinitis. This article provides evidence-based strategies for reducing exposure to indoor and outdoor allergens, improving symptom control.

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Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Related Experiment Videos

Last Updated: Jul 6, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Area of Science:

  • Allergy and Immunology
  • Environmental Health

Background:

  • Environmental controls are crucial for allergic rhinitis management.
  • Past recommendations relied on common sense and antigen reduction, not direct symptom correlation.
  • Current strategies need to be based on specific allergen sensitivities.

Purpose of the Study:

  • To detail current recommendations for reducing antigen exposure in allergic rhinitis.
  • To present evidence-based strategies for environmental control based on specific sensitivities.

Main Methods:

  • Review of current literature on environmental controls for allergic rhinitis.
  • Identification of effective strategies for reducing indoor inhalant allergens (dust mites, cockroach, molds, pet danders).
  • Identification of effective strategies for reducing outdoor inhalant allergens.

Main Results:

  • Provides specific recommendations for reducing exposure to common indoor allergens.
  • Offers techniques for minimizing exposure to outdoor allergens.
  • Emphasizes the importance of tailoring environmental controls to individual sensitivities.

Conclusions:

  • Evidence-based environmental control strategies are essential for effective allergic rhinitis management.
  • Reducing antigen exposure, tailored to specific sensitivities, can improve patient outcomes.
  • This article offers a comprehensive guide to indoor and outdoor allergen reduction techniques.