Related Experiment Video
Updated: Jul 6, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Nutritional status, breastfeeding, and evolution of Infants with acute viral bronchiolitis
Cristina T L Dornelles1, Jefferson P Piva, Paulo J C Marostica
1Nutrition Departament, Hospital de Clínicas de Porto Alegre/RS, Rua: Ramiro Barcelos, 2350, 90035903-Porto Alegre-RS, Brazil. cleal@hcpa.ufrgs.br
Insights
Exclusive breastfeeding duration is linked to better outcomes for infants with acute viral bronchiolitis. Longer exclusive breastfeeding reduces hospital stay and oxygen use in infants with this common respiratory illness.
Area of Science:
- Pediatrics
- Infectious Diseases
- Nutrition
Background:
- Acute viral bronchiolitis is a frequent respiratory infection in infants.
- Nutritional status and breastfeeding practices may influence disease severity.
- Understanding risk factors is crucial for managing infant respiratory illnesses.
Purpose of the Study:
- To assess nutritional and breastfeeding status in infants with acute viral bronchiolitis.
- To identify risk factors for unfavorable clinical outcomes in these infants.
- To evaluate the relationship between feeding practices and disease severity.
Main Methods:
- Prospective study of 175 infants up to six months old with acute viral bronchiolitis.
- Viral diagnosis via immunofluorescence test and nutritional assessment using anthropometry.
- Outcomes measured included oxygen use duration, hospital stay length, and unit type.
Main Results:
- Nutritional status did not significantly impact the clinical course of acute viral bronchiolitis.
- Exclusive breastfeeding duration was inversely related to oxygen use and hospital stay length.
- Shorter exclusive breastfeeding correlated with higher care unit admission (pediatric ward or ICU).
Conclusions:
- Longer duration of exclusive breastfeeding is associated with improved clinical outcomes in infants with acute viral bronchiolitis.
- Nutritional status alone did not predict disease severity in this cohort.
- Promoting exclusive breastfeeding may mitigate the severity and duration of illness in infants.
Abstract:
Acute viral bronchiolitis is a common respiratory infectious disease of infancy. A prospective study was carried out with 175 infants aged up to six months to evaluate their nutritional and breastfeeding status as possible risk factors for unfavourable evolution of previously-healthy infants from a care hospital. Immunofluorescence test for virus and anthropometric assessment were performed. Outcomes were length of oxygen-use, length of hospital stay, and type of hospital unit needed. Seventy-three percent of the infants were well-nourished, 6% undernourished, 8.6% at a nutritional risk, 10.9% overweight, and 1.7% obese. Eighty-one percent of the undernourished and nutritionally at-risk infants and 72% of the well-nourished, overweight, and obese infants did not receive exclusive breastfeeding. The median length of hospital stay was four days and of oxygen-use was 60 hours. The nutritional status did not affect the clinical course of previously-healthy infants with acute viral brochiolitis. The duration of exclusive breastfeeding, but not type of breastfeeding, was inversely related to the length of oxygen-use and the length of hospital stay. Shorter exclusive breastfeeding was observed in infants who were assigned to a paediatric ward or to an intensive care unit. In conclusion, longer duration of breastfeeding was associated with better clinical outcomes.
More Related Videos
08:12Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
09:36Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
Related Concept Videos
Respiratory Syncytial Virus Disease
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Development of Human Microbiota
Development of the Oral Microbiota
Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include: