Pituitary adenoma associated with intraventricular meningioma: case report

Leodante B da Costa1, Jay Riva-Cambrin, Asheesh Tandon

  • 1Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada.

Insights

This report details a rare case of a prolactin-secreting pituitary adenoma co-occurring with a fourth ventricle meningioma. The patient underwent surgical removal of the meningioma and medical management for the pituitary adenoma.

Area of Science:

  • Neuro-oncology
  • Endocrinology

Background:

  • Intracranial meningiomas and pituitary adenomas can rarely co-occur.
  • Intraventricular meningiomas are uncommon, with those in the fourth ventricle being exceptionally rare.

Observation:

  • A patient presented with both a prolactin-secreting pituitary adenoma and a fourth ventricle meningioma.
  • This dual diagnosis represents a highly unusual clinical presentation.

Findings:

  • The patient received surgical resection for the fourth ventricle meningioma.
  • Medical treatment was administered for the prolactin-secreting pituitary adenoma.

Implications:

  • This case highlights the possibility of concurrent meningioma and pituitary adenoma, even in rare locations.
  • Further investigation into the potential mechanisms underlying such associations may be warranted.

Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...