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[Optimized programming during cardiac resynchronization therapy].

T Deneke1, B Lemke, M Horlitz

  • 1Herzzentrum der Ruhr-Universität Bochum, BG Universitätsklinik Bergmannsheil Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany. thomas.deneke@rub.de

Herzschrittmachertherapie & Elektrophysiologie
|March 12, 2008
PubMed
Summary
This summary is machine-generated.

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Optimizing cardiac resynchronization therapy (CRT) programming with atrioventricular (AV) and ventriculoventricular (VV) delays improves heart failure outcomes. This approach enhances hemodynamic function and clinical efficacy in patients with refractory heart failure.

Area of Science:

  • Cardiology
  • Biomedical Engineering

Context:

  • Cardiac resynchronization therapy (CRT) is an established treatment for refractory heart failure.
  • Optimizing CRT programming parameters, specifically atrioventricular (AV) and ventriculoventricular (VV) delays, can significantly enhance therapeutic efficacy and hemodynamic performance.

Purpose:

  • To discuss various methods for determining optimal AV and VV delays in CRT systems.
  • To present a pragmatic approach for optimizing CRT programming to improve patient outcomes.

Summary:

  • The manuscript details techniques for optimizing VV delay, including electrocardiographic criteria and Doppler echocardiography to assess ventricular pre-excitation and ejection timing.
  • Optimal AV delay is determined using Doppler echocardiography and a formula to achieve synchronized left atrial contraction and left ventricular ejection.

Related Experiment Videos

  • A practical, efficient method for enhancing CRT performance is described, with recommendations for re-optimization when heart failure worsens or left ventricular dimensions change.

    • Impact:

    • Improved clinical and hemodynamic outcomes for patients with heart failure undergoing CRT.
    • Enhanced understanding and application of programming strategies for CRT devices.
    • Potential for increased CRT device effectiveness and patient quality of life.