The management of leiomyoma uteri by GnRH analogues

Therapy with GnRH analogs is the first medical solution to be really effective in treating uterine fibromas, even if with limited and temporary benefits. Out of the 12 patients treated the Authors observed that a 60% reduction of the volume of the uterus can be achieved after 3-6 months therapy, with rapid recuperation of the initial volume after interruption of the treatment. It is therefore preferable to use GnRH analogs as a propedeutic therapy rather than surgery.