Combining group-based trajectory modeling and propensity score matching for causal inferences in nonexperimental longitudinal data
Related Experiment Video
Updated: Jul 6, 2026

Inverse Probability of Treatment Weighting (Propensity Score) using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Amelia Haviland1, Daniel S Nagin, Paul R Rosenbaum
1Rand Corporation, Pittsburg, PA, USA.
Abstract:
A central theme of research on human development and psychopathology is whether a therapeutic intervention or a turning-point event, such as a family break-up, alters the trajectory of the behavior under study. This article describes and applies a method for using observational longitudinal data to make more transparent causal inferences about the impact of such events on developmental trajectories. The method combines 2 distinct lines of research: work on the use of finite mixture modeling to analyze developmental trajectories and work on propensity score matching. The propensity scores are used to balance observed covariates and the trajectory groups are used to control pretreatment measures of response. The trajectory groups also aid in characterizing classes of subjects for which no good matches are available. The approach is demonstrated with an analysis of the impact of gang membership on violent delinquency based on data from a large longitudinal study conducted in Montréal, Canada.
Related Concept Videos
Comparing the Survival Analysis of Two or More Groups
Strategies for Assessing and Addressing Confounding
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Longitudinal Studies
Study Design in Statistics
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Statistical Inference Techniques in Hypothesis Testing: Parametric Versus Nonparametric Data
Parametric statistics, as the name suggests, assumes that data follow a specific distribution, often a normal distribution. This assumption enables robust hypothesis testing and estimation. Parametric methods, like the Student's t-test or Goodness-of-fit test, are frequently employed in biostatistics due to their robustness. For instance, comparing...
Causality in Epidemiology
