Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Synchronous Double Cancer of Left Lung and Esophagus Which Was Performed Simultaneous Resection].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same author

Recurrence of gastric adenocarcinoma of fundic-gland mucosa type with black spots after endoscopic submucosal dissection and oral proton pump inhibitor discontinuation.

Pathology international·2022
Same author

[Thoracoscopic Surgery by Thin Thoracoscope with Fine Needlescopic Forceps for Cavernous Hemangioma in the Chest Wall].

Kyobu geka. The Japanese journal of thoracic surgery·2021
Same author

Verification of the eighth edition of the UICC-TNM classification on surgically resected lung adenocarcinoma: Comparison with previous classification in a local center.

Cancer reports (Hoboken, N.J.)·2021
Same author

[Surgical Treatment to Bilateral Multiple Primary Lung Cancer Patients].

Kyobu geka. The Japanese journal of thoracic surgery·2021
Same author

Thoracic extradural malignant melanoma with unknown primary.

BJR case reports·2020

Related Experiment Video

Updated: Jul 6, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
08:20

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

[Case with diffuse duodenitis and enteritis following total colectomy for ulcerative colitis].

Mayuki Nakajima1, Hisayuki Nakashima, Kaoru Kiyohara

  • 1Department of Surgery, Tonami General Hospital.

Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|March 12, 2008
PubMed
Summary

A patient with ulcerative colitis experienced severe gastrointestinal bleeding and inflammation after surgery. Intravenous dexamethasone effectively treated the condition when other therapies failed.

More Related Videos

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
04:05

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

Published on: May 31, 2024

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Related Experiment Videos

Last Updated: Jul 6, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
08:20

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
04:05

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

Published on: May 31, 2024

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Inflammatory Bowel Disease

Background:

  • A 25-year-old woman with a four-year history of pancolonic ulcerative colitis (UC) underwent surgery.
  • The patient developed severe postoperative complications including abdominal pain, fever, and bloody diarrhea.

Observation:

  • Computed tomography revealed duodenal and small intestinal wall thickening.
  • Endoscopic examination showed diffuse mucosal edema, redness, erosion, and ulceration in the duodenum, small intestine, and ileal pouch, resembling UC.
  • The patient experienced five episodes of massive melena.

Findings:

  • Transcatheter arterial embolization successfully managed the massive melena.
  • Antibiotics and prednisolone were ineffective in reducing lesion activity.
  • Intravenous dexamethasone administration led to symptom improvement and resolution of endoscopic findings.

Implications:

  • This case highlights a rare postoperative complication of restorative proctocolectomy in ulcerative colitis patients.
  • Intravenous dexamethasone may be an effective treatment for severe gastrointestinal inflammation and bleeding post-surgery.
  • Further research is warranted to understand the mechanism and optimize management strategies for such cases.