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Liver resection in octogenarians.

F Riffat1, F Chu, D L Morris

  • 1UNSW Department of Surgery, St George Hospital, Sydney, Australia.

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
|March 12, 2008
PubMed
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Liver resection is safe for octogenarians, with low mortality and acceptable morbidity in carefully selected patients. This study analyzed outcomes in this growing elderly population undergoing liver surgery.

Area of Science:

  • Hepatobiliary Surgery
  • Geriatric Surgery
  • Oncology

Background:

  • Liver resections are increasingly performed in elderly patients.
  • Limited data exists on the operative safety of liver resection in octogenarians.
  • Octogenarians represent a rapidly growing demographic segment.

Purpose of the Study:

  • To analyze the safety and outcomes of liver resection in octogenarians.
  • To evaluate peri-operative mortality and morbidity in this patient group.
  • To compare results with younger patient cohorts.

Main Methods:

  • Prospective data collection and retrospective case note analysis.
  • Study period: 1999-2004 in a tertiary referral liver surgery unit.
  • Primary outcome: 30-day mortality; secondary outcome: post-operative complications.

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Main Results:

  • 15 octogenarians (median age 82) underwent liver resection.
  • One peri-operative mortality; all patients alive at 1, 3, and 6 months.
  • 27% experienced major surgical complications; 20% had exacerbations of comorbidities.

Conclusions:

  • Liver resection is safe in carefully selected octogenarians.
  • Tertiary referral centers can achieve low mortality and acceptable morbidity.
  • Outcomes support the feasibility of liver surgery in this elderly demographic.