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Delayed embryo transfer in an in-vitro fertilization programme: how to avoid working on Sunday
J Belaisch-Allart1, P Briot, J P Allart
1Department of Obstetrics and Gynaecology, Hospital Boucicaut, Paris, France.
Human Reproduction (Oxford, England)
|April 1, 1991
Summary
Gonadotropin-releasing hormone analogues enable delayed human chorionic gonadotropin (HCG) administration and weekend oocyte retrievals. This study shows delaying embryo transfers from Friday to Monday also maintains results, improving assisted reproduction cost-effectiveness.
Area of Science:
- Reproductive Endocrinology
- Assisted Reproductive Technology
Background:
- Gonadotropin-releasing hormone (GnRH) analogues are used in assisted reproduction to control ovulation timing.
- Current protocols often necessitate weekend oocyte retrievals due to fixed treatment schedules.
Purpose of the Study:
- To investigate the feasibility of avoiding Sunday embryo transfers in assisted reproduction programs.
- To assess the impact of delaying embryo transfers on treatment outcomes.
Main Methods:
- Utilizing GnRH analogues to manage the timing of human chorionic gonadotropin (HCG) administration.
- Implementing a protocol to delay embryo transfers for patients with Friday oocyte retrievals until Monday.
- Comparing pregnancy and implantation rates between delayed and non-delayed transfer groups.
Main Results:
- Delaying embryo transfers from Friday to Monday did not significantly alter pregnancy or implantation rates.
- The strategy successfully avoided Sunday embryo transfers.
- This scheduling flexibility enhances operational efficiency in fertility clinics.
Conclusions:
- Assisted reproduction programs can implement flexible embryo transfer scheduling without compromising clinical outcomes.
- Avoiding weekend embryo transfers improves the cost-effectiveness and logistical management of fertility treatments.
- GnRH analogue use combined with flexible transfer timing optimizes assisted reproduction program efficiency.