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Updated: Jul 6, 2026
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
In vitro analysis of cisplatin functionalized magnetic nanoparticles in combined cancer chemotherapy and
M Babincov1, V Altanerov, C Altaner
1Department of Nuclear Physics and Biophysics, Comenius University, Bratislava, Slovakia. babincova@fmph.uniba.sk
Abstract:
A novel platform has been developed for combined cancer chemotherapy and hyperthermia based on iron oxide magnetic nanoparticles functionalized with cis-diamminedichloroplatinum(II) (cisplatin). The capabilities of this system for heating and controlled drug release were investigated, and the system was tested in vitro by the treatment of BP6 rat sarcoma cells, where we demonstrated a synergism between the effects of cisplatin-targetMAG nanoparticles and the application of electromagnetic field.
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