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Published on: September 23, 2015
Serotonin syndrome following cardiac surgery
Ganesh Shanmugam1, Blaine Kent, Turki Alsaiwadi
1Department of Cardiac Surgery, QEII Health Sciences Centre, Halifax Infirmary, 1796 Summer Street, Halifax, Nova Scotia B3L 4P7, Canada. sgunpat@hotmail.com
Selective serotonin reuptake inhibitors (SSRIs), used for depression, can cause serotonin syndrome after cardiac surgery. This rare but potentially fatal condition requires early recognition and management, especially with polypharmacy.
Area of Science:
- Pharmacology
- Cardiology
- Neurology
Background:
- Selective serotonin reuptuptake inhibitors (SSRIs) are common antidepressants.
- Cardiac surgery involves complex peri-operative medication management.
Observation:
- A rare case of serotonin syndrome occurred post-cardiac surgery.
- The patient presented with specific clinical features requiring diagnosis.
Findings:
- Serotonin syndrome is an underreported complication in cardiac surgery patients.
- Polypharmacy increases the risk of drug interactions with SSRIs.
Implications:
- Clinicians must consider SSRI interactions in cardiac surgery patients.
- Early diagnosis and prompt treatment are crucial for managing this potentially fatal syndrome.
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