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Asthma in patients with atopic dermatitis.
Z Pourpak1, H Mozaffari, M Gharagozlou
1Immunology, Asthma and Allergy Research Institute and Department of Clinical Immunology and Allergy, Children Medical Center, Medical Sciences/ University of Tehran, Tehran, Iran. pourpakz@sina.tums.ac.ir
Indian Journal of Pediatrics
|March 13, 2008
Summary
Asthma occurs in over a quarter of patients with atopic dermatitis (AD). While AD is a significant risk factor for asthma development, the exact causes remain unclear.
Area of Science:
- Pediatric Allergy and Immunology
- Dermatology
- Respiratory Medicine
Background:
- Atopic dermatitis (AD) is a chronic inflammatory skin condition.
- Asthma is a common respiratory condition often linked with allergic diseases.
- Understanding the relationship between AD and asthma is crucial for comprehensive patient care.
Purpose of the Study:
- To determine the prevalence of asthma in children diagnosed with atopic dermatitis.
- To identify potential factors associated with the co-occurrence of asthma in AD patients.
Main Methods:
- A cross-sectional study involving 236 patients with atopic dermatitis (AD).
- Diagnosis of AD based on Hanifin & Rajka criteria; severity assessed using the SCORAD index.
- Asthma diagnosis confirmed via medical history and clinical examination, focusing on respiratory symptoms.
Main Results:
- The frequency of asthma among patients with AD was found to be 27.5%.
- No significant differences were observed in SCORAD index, breastfeeding duration, serum IgE levels, or blood eosinophil counts between asthmatic and non-asthmatic AD patients.
- The mean age of AD patients was 38.67 months, with asthma onset around 20 months.
Conclusions:
- Atopic dermatitis is a significant predisposing factor for developing asthma.
- The prevalence of asthma in AD patients is higher than in the general population.
- Further research is needed to elucidate the specific causative factors linking AD and asthma.
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