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Pediatric extradural spinal tumors.

Raj Kumar1, Pramod J Giri

  • 1Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. rajkumar@sgpgi.ac.in

Pediatric Neurosurgery
|March 13, 2008
PubMed
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This study analyzed 16 pediatric extradural spinal tumors, finding that surgical intervention and adjuvant therapy significantly improved functional outcomes in most patients. Long-term follow-up revealed varied histopathological presentations and treatment responses.

Area of Science:

  • Pediatric Oncology
  • Neurosurgery
  • Spinal Tumors

Background:

  • Extradural spinal tumors in children are rare but can cause significant morbidity.
  • Understanding treatment outcomes and histopathological variations is crucial for effective management.
  • Data from India on pediatric spinal tumors is limited.

Purpose of the Study:

  • To review and evaluate pediatric extradural spinal tumors treated at a tertiary care center in India.
  • To analyze clinical presentation, radiological findings, surgical approaches, and histopathological variations.
  • To assess functional outcomes using the McCormick Functional Grading System.

Main Methods:

  • Retrospective review of 16 pediatric patients with extradural spinal tumors (1998-2006).
  • Evaluation of symptom duration, clinical signs, radiological investigations, and surgical techniques.

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  • Histopathological analysis and functional grading (McCormick System) pre- and post-operatively.

    • Main Results:

    • A total of 16 children (11 boys, 5 girls; age 3-20 years) were treated.
    • Symptom duration averaged 9.5 months for benign and 4.2 months for malignant tumors.
    • Significant functional improvement observed: 74% presented with Grade III-IV, reducing to 35% at follow-up.

    Conclusions:

    • Surgical management combined with adjuvant chemoradiotherapy, when indicated, leads to significant functional recovery in pediatric extradural spinal tumors.
    • Diverse histopathological variants were observed, highlighting the need for tailored treatment strategies.
    • This study provides valuable insights into the management of pediatric spinal tumors in the Indian subcontinent.