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Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
Radical prostatectomy for high-risk prostate cancer
Ofer Yossepowitch1, James A Eastham
1Department of Urology, Rabin Medical Center, Petah-Tikva, 49726, Israel. oferyoss@netvision.net.il
World Journal of Urology
|March 13, 2008
Summary
Men with high-risk prostate cancer should not be excluded from radical prostatectomy (RP). Evidence shows RP offers good outcomes and similar risks compared to lower-risk cases, improving cancer control and quality of life.
Area of Science:
- Urology
- Oncology
Background:
- Lack of consensus exists for identifying and treating men with high-risk, organ-confined prostate cancer.
- High-risk prostate cancer patients are traditionally steered away from radical prostatectomy (RP).
Purpose of the Study:
- To analyze the literature on high-risk prostate cancer, its historical context, risk stratification, and outcomes after RP.
- To evaluate the suitability of RP for men with clinically localized high-risk prostate cancer.
Main Methods:
- A comprehensive literature search was conducted using MEDLINE/PubMed for studies on high-risk prostate cancer.
- Analysis focused on historical evolution, current risk stratification, treatment guidelines, and outcomes post-RP.
Main Results:
- Contemporary evidence indicates that high-risk prostate cancer patients often have favorable prognoses after RP.
- Many clinically high-risk cancers are pathologically confined to the prostate, with most patients remaining cancer-free post-RP.
- RP in high-risk patients shows comparable morbidity to that in lower-risk groups.
Conclusions:
- Men with clinically localized high-risk prostate cancer should be considered for radical prostatectomy (RP).
- Refined surgical techniques can enhance cancer control rates and minimize adverse effects on quality of life following RP.
