Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular findings in Down's syndrome.

A Hestnes1, T Sand, K Fostad

  • 1Hallsetheimen, Central Institution for the Mentally Retarded, Klaebu, Norway.

Journal of Mental Deficiency Research
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Harnessing historical data to derive reference limits - A comparison of e-norms to traditionally derived reference limits.

Clinical neurophysiology practice·2024
Same author

Evening light environments can be designed to consolidate and increase the duration of REM-sleep.

Scientific reports·2022
Same author

Shift work, inflammation and musculoskeletal pain-The HUNT Study.

Occupational medicine (Oxford, England)·2021
Same author

Experimental sleep restriction increases latency jitter in pain elicited cortical responses.

Heliyon·2021
Same author

A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders.

Scientific reports·2020
Same author

The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study.

Sleep medicine·2018

Patients with Down syndrome (DS) frequently experience ocular issues. This study found a high prevalence of keratoconus in adults with DS, with most patients showing significant ocular abnormalities.

Area of Science:

  • Ophthalmology
  • Genetics
  • Medical Research

Background:

  • Down syndrome (DS) is associated with various health complications, including ocular abnormalities.
  • Previous research has documented a range of eye conditions in individuals with DS.
  • Understanding the specific ocular profile in institutionalized adult populations with DS is crucial for targeted care.

Purpose of the Study:

  • To document and analyze the ocular findings in a cohort of adult patients with Down syndrome residing in a specific institution.
  • To compare the ocular status of patients with DS to a matched control group of mentally retarded individuals without DS.
  • To identify any unusual or particularly prevalent ocular conditions within this specific DS population.

Main Methods:

  • Ophthalmic examinations were conducted on 30 adult patients with Down syndrome.

Related Experiment Videos

  • A control group of mentally retarded individuals without DS from the same institution was selected for comparison.
  • Data on ocular findings were collected and analyzed for both groups.

    • Main Results:

    • A high incidence of ocular abnormalities was observed in the Down syndrome group, with only one patient having nearly normal ocular status.
    • Nine out of 30 patients (30%) with Down syndrome were diagnosed with keratoconus, a significantly high prevalence.
    • The findings largely confirmed previously reported ocular issues in Down syndrome populations.

    Conclusions:

    • Adults with Down syndrome, particularly those in institutional settings, exhibit a high burden of ocular disease.
    • Keratoconus appears to be unusually prevalent in this specific institutionalized adult Down syndrome cohort.
    • Comprehensive and regular ophthalmic screening is essential for individuals with Down syndrome to detect and manage sight-threatening conditions early.