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Related Experiment Video

Updated: Jul 6, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

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Published on: October 24, 2018

The theory-practice gap: ECMO research example.

Denis Anthony1, Graham Lawson, Doreen Crawford

  • 1Mary Seacole Research Centre, De Montfort University, Leicester, UK.

Paediatric Nursing
|March 14, 2008
PubMed
Summary
This summary is machine-generated.

It takes years for Extracorporeal Membrane Oxygenation (ECMO) research on drug delivery to reach nursing texts. This delay hinders nurses from accessing vital information for evidence-based practice.

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Last Updated: Jul 6, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

Area of Science:

  • Pharmacology
  • Clinical Practice
  • Medical Education

Background:

  • The translation of research findings into clinical practice is often slow.
  • A significant time lag exists between research identifying issues and their inclusion in medical and nursing literature.
  • Extracorporeal Membrane Oxygenation (ECMO) serves as a case study to investigate this dissemination gap, particularly concerning its effects on medication.

Purpose of the Study:

  • To examine the extent to which nursing journals and textbooks discuss the effects of ECMO on medication.
  • To assess the time lag between the identification of ECMO's impact on drug pharmacokinetics and its discussion in clinical literature.

Main Methods:

  • A systematic review was conducted on literature identifying pharmacokinetic alterations in ECMO patients.
  • Searched Medline for research on drug delivery in ECMO and CINAHL for dissemination to nurses.
  • Reviewed neonatal nursing and pediatric intensive care textbooks for sections on ECMO.

Main Results:

  • Studies on altered drug delivery in ECMO patients date back to 1989.
  • Only three papers accessible to clinicians addressed ECMO's effect on drug delivery.
  • Two textbooks discussed these issues, but with an eight-year delay from the initial research publication.

Conclusions:

  • Nurses relying solely on textbooks may miss the latest research on ECMO and medication.
  • Advanced education in critical appraisal and literature searching is crucial for nurses.
  • Master's level education can equip nurses with skills for evidence-based practice in areas like ECMO care.