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Pallidal deep brain stimulation in the treatment of Meige syndrome
P Blomstedt1, S Tisch, M I Hariz
1Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden. patric.blomstedt@neuro.umu.se
Background:
Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published.
Methods/Results:
We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished.
Conclusions:
The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.
