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Updated: Jul 6, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

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Published on: March 11, 2021

[Accelerated partial breast irradiation in 2008: interrogations and perspectives].

J-M Hannoun-Levi¹, D Azria, Y Belkacémi

¹Département de radiothérapie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France. jean-michel.hannoun-levi@nice.fnclcc.fr

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique

|March 14, 2008

Summary

Accelerated partial breast irradiation (APBI) is becoming a mature treatment option, with ongoing trials comparing it to whole breast irradiation (WBI). Results are anticipated to establish APBI

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Area of Science:

Oncology
Radiotherapy
Clinical Trials

Context:

Accelerated partial breast irradiation (APBI) has advanced significantly since 2000, incorporating sophisticated technologies.
Multiple international phase III trials are currently underway to evaluate APBI.
These trials aim to demonstrate the equivalence of APBI and whole breast irradiation (WBI) regarding local control.

Purpose:

To analyze the advantages and ongoing questions surrounding APBI.
To discuss the challenges faced by radiation oncologists and patients awaiting long-term results from phase III trials.
To position APBI within the landscape of breast cancer treatment options.

Summary:

APBI is evolving with advanced technologies, supported by numerous ongoing international phase III trials.
The primary objective of these trials is to establish local control equivalence between APBI and WBI.
The analysis addresses the benefits, uncertainties, and patient/clinician perspectives on APBI adoption.

Impact:

APBI is expected to become a standard treatment option alongside WBI, similar to how conservative treatments evolved.
The rigorous management of differing clinical investigation conditions is crucial for APBI's integration.
Anticipated trial outcomes will clarify APBI's role in breast cancer management.