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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Medico-legal aspects of mesothelioma
Sara Partemi1, Fabio De Giorgio
1Institute of Legal Medicine, Catholic University of the Sacred Heart, School of Medicine, Rome, Italy. sara.partemi@rm.unicatt.it
Abstract:
The Authors, reviewing the Literature on asbestos-related Malignant Mesothelioma (MM), found that because of its very peculiar characteristics, the causal link between professional asbestos exposure and the development of this tumour is very difficult to define in respect to: diagnosis, causal link and individuation of possible culpable conducts. The evaluation of causal link in different medico-legal areas is studied by different criteria. In civil law the criterion of weak causality is followed to allow compensation for damages. For institutional purposes in INAIL, the definition of causal link is particularly facilitated by the legal presumption of origin. In fact it is sufficient, that asbestos-related lesions are ascertained in individuals who are or were exposed at any time of their professional life to the risk of inhaling asbestos fibres. In criminal law, the current approach of the Supreme Court is to demand evidence of strong causality, with a high logical probability and rational credibility, and beyond reasonable doubt, because criminal liability is personal as established in article 27 of the Italian Constitution. It is worth pointing out that all the levels of evidence indicated above must pass the test of scientific suitability or possibility.
Insights
Establishing a causal link between asbestos exposure and malignant mesothelioma is complex. Legal and medical criteria vary significantly across civil, institutional, and criminal law contexts.
Area of Science:
- Occupational Health
- Legal Medicine
- Oncology
Background:
- Malignant mesothelioma (MM) is strongly linked to asbestos exposure.
- Defining the causal link between occupational asbestos exposure and MM presents diagnostic and legal challenges.
Purpose of the Study:
- To review the literature on the medico-legal definition of causality in asbestos-related malignant mesothelioma.
- To analyze the varying criteria for establishing a causal link in different legal frameworks.
Main Methods:
- Literature review of scientific and legal texts.
- Comparative analysis of medico-legal standards for causality assessment.
Main Results:
- Civil law utilizes a 'weak causality' standard for compensation.
- Institutional frameworks (e.g., INAIL) employ a facilitated 'legal presumption of origin' for asbestos-related lesions.
- Criminal law requires 'strong causality,' demonstrating high logical probability and rational credibility, consistent with Italian constitutional law.
Conclusions:
- The definition and evaluation of causality in asbestos-related MM differ significantly across legal domains.
- Scientific suitability is a critical factor in all causality assessments.
- Standardizing criteria remains a challenge in addressing asbestos-related diseases in legal contexts.
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