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Disease perceptions among people with Crohn's disease
Sunanda V Kane1, Edward V Loftus, Marla C Dubinsky
1Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. kane.sunanda@mayo.edu
Inflammatory Bowel Diseases
|March 15, 2008
Summary
Patient perceptions of Crohn's disease (CD) severity often differ from objective measures. Understanding these perceptions is key for improving patient care and treatment decisions.
Area of Science:
- Gastroenterology
- Patient-Reported Outcomes
- Inflammatory Bowel Disease Research
Background:
- The relationship between patient-perceived disease course and objective symptom severity in Crohn's disease (CD) is not well understood.
- Previous research has not fully explored how CD patients' views on their overall disease trajectory align with current symptom-based assessments.
Purpose of the Study:
- To characterize Crohn's disease patient perceptions of their overall disease course and current symptomatology using an objective symptom scale.
- To investigate the correlation between patients' perceived disease course and their current, objectively measured symptoms.
Main Methods:
- A telephone screening identified eligible patients for an online survey.
- 1205 patients completed a self-administered online survey assessing disease perceptions and symptoms.
Main Results:
- Patient-reported overall disease course (mild 16%, moderate 50%, severe 34%) poorly correlated with objective symptom measures.
- Perceived current symptomatology (mild 61%, moderate 29%, severe 10%) showed a significant disconnect with the perceived overall disease course.
- A majority of patients perceived their overall disease course as more severe than indicated by their current symptoms.
Conclusions:
- Patient perceptions of overall disease severity may not align with objective measures of current disease activity.
- Incorporating a comprehensive understanding of patients' perceptions of both overall disease course and current symptoms can inform treatment decisions.
- Improved appreciation of patient perspectives may enhance the quality of care for individuals with Crohn's disease.
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