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Updated: Jul 6, 2026
11:07
Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
Published on: December 19, 2014
[Cryptococcosis and pets]
Gemma Castellá1, M Lourdes Abarca, F Javier Cabañes
1Grup de Micologia Veterinària, Departament de Sanitat i d' Anatomia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Spain. Gemma.Castella@uab.es
Revista Iberoamericana De Micologia
|March 15, 2008
Summary
Cryptococcosis, a fungal infection caused by Cryptococcus neoformans and Cryptococcus gattii, is uncommon in domestic animals but frequently affects cats. This review covers feline and canine cryptococcosis, including diagnosis, treatment, and public health relevance.
Area of Science:
- Veterinary Mycology
- Infectious Diseases in Animals
Background:
- Cryptococcosis is a mycosis caused by Cryptococcus neoformans and Cryptococcus gattii.
- While uncommon and sporadic in domestic animals, it is frequently reported in cats.
Purpose of the Study:
- To review feline and canine cryptococcosis.
- To discuss clinical signs, disease forms, diagnosis, and treatment.
- To address the prevalence in Spain and its zoonotic potential.
Main Methods:
- Literature review of cryptococcosis in domestic animals.
- Focus on clinical aspects, diagnostics, and therapeutics.
- Epidemiological and public health considerations.
Main Results:
- Cats are the most commonly affected domestic animals.
- Diagnosis involves cytologic examination, antigen detection, and culture.
- Treatment strategies and therapeutic agents are discussed.
Conclusions:
- Cryptococcosis requires careful diagnosis and management in cats and dogs.
- Understanding its zoonotic potential is crucial for public health.
- Further epidemiological data from Spain is needed.
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