Pentoxifylline to treat radiation proctitis: a small and inconclusive randomised trial
R Venkitaraman1, A Price, J Coffey
1Academic Urology Unit, The Institute of Cancer Research and Royal Marsden Hospital, Sutton, UK.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|March 15, 2008
Abstract:
This prospective randomised controlled study of 40 patients could not show a statistically significant advantage with 6 months of pentoxifylline compared with standard measures for late radiation-induced rectal bleeding. However, a modest benefit cannot be excluded and larger randomised placebo-controlled trials with longer durations of pentoxifylline treatment may be justified.
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