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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

Use of enoxaparin in patients undergoing percutaneous coronary intervention

Rajan A Kadakia1, James J Ferguson

  • 1St. Luke's Episcopal Hospital, Texas Heart Institute, Baylor College of Medicine, Houston, Texas 77225, USA.

Critical Pathways in Cardiology
|March 15, 2008
PubMed

Insights

Enoxaparin shows improved outcomes in acute coronary syndromes, but managing patients needing coronary intervention requires specific strategies. This study outlines four approaches for enoxaparin transition to the catheterization lab.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Enoxaparin use is supported by large trials for acute coronary syndromes.
  • Guidelines now include enoxaparin for unstable angina/non-ST elevation myocardial infarction.
  • Managing patients on enoxaparin before coronary intervention presents challenges.

Purpose of the Study:

  • To present management strategies for patients on subcutaneous enoxaparin undergoing coronary intervention.
  • To provide specific enoxaparin dosing recommendations in this setting.

Main Methods:

  • Review of clinical trial evidence.
  • Development of four distinct management strategies.
  • Formulation of dosing recommendations for catheterization laboratory transition.

Main Results:

  • Four potential management strategies are detailed.
  • Specific enoxaparin dosing guidelines are proposed for procedural management.

Conclusions:

  • Effective management strategies are crucial for patients on enoxaparin requiring coronary intervention.
  • Standardized dosing recommendations can optimize care during transition to the catheterization lab.

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