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Updated: Jul 6, 2026

Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
Published on: June 20, 2018
[Chronic rhinosinusitis with septal perforation. Differential diagnostic considerations]
W Mann1, P Bumb, E Märker-Hermann
1HNO-Klinik und Poliklinik der Johannes-Gutenberg-Universität Mainz, Langenbeckstrasse 1, 55131 Mainz, Deutschland. Mann@hno.klinik.uni-mainz.de
Abstract:
Chronic rhinosinusitis together with nasal septal perforation with or without pain of the nasal skeleton and without previous trauma or surgery point toward the possible diagnosis of Wegener's granulomatosis. However, nasal biopsy and serologic testing remain inconclusive in many patients. The otolaryngologist's role in this situation is to initiate, in close cooperation with a rheumatologist, therapy with sulfatrimethoprim, as well as with immunosuppressants if necessary. This helps stabilize the symptomatology and may prevent progressive systemic disease.
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