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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

[Efficacy of cardiac resynchronization therapy-defibrillator for treating patients with chronic heart disease]

Wei Hua1, Shu Zhang, Fang-Zheng Wang

  • 1Cardiac Arrhythmia Center, Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.

Zhonghua Xin Xue Guan Bing Za Zhi
|March 18, 2008
PubMed

Insights

Cardiac resynchronization therapy-defibrillator (CRT-D) implantation is safe and effective for chronic heart failure patients. This therapy improved cardiac function and reduced sudden cardiac death risk in a one-year follow-up.

Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Context:

  • Chronic heart failure (CHF) significantly impacts patient quality of life and survival.
  • Drug-refractory heart failure presents a therapeutic challenge.
  • Sudden cardiac death remains a major concern in heart failure patients.

Purpose:

  • To evaluate the clinical efficacy and safety of cardiac resynchronization therapy-defibrillator (CRT-D) in patients with chronic, drug-refractory heart failure.
  • To assess the impact of CRT-D implantation on cardiac function and mortality over a one-year period.

Summary:

  • Seventeen patients with drug-refractory heart failure (12 dilated cardiomyopathy, 5 ischemic heart disease) underwent CRT-D implantation.
  • Successful implantation was achieved in all patients with no complications.
  • Over a mean 13-month follow-up, no deaths occurred, left ventricular function improved, and CRT-D successfully managed ventricular arrhythmias.

Impact:

  • CRT-D implantation is a feasible and safe treatment option for selected refractory heart failure patients.
  • The therapy is associated with improved cardiac function.
  • CRT-D implantation demonstrates a reduced risk of sudden cardiac death in this patient cohort.
Abstract

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