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[Update on vascular dementias].

S Auriacombe1, P Amarenco, J-C Baron

  • 1Centre mémoire de ressource et de recherche, hôpital Pellegrin, bâtiment USN Tastet-Girard, 33076 Bordeaux cedex, France. sophie.auriacombe@u-bordeaux2.fr

Revue Neurologique
|March 18, 2008
PubMed
Summary
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Vascular dementia concepts have evolved, expanding to include vascular cognitive impairment and disorders beyond dementia. This review covers diagnosis, epidemiology, and links to Alzheimer's disease, with a look at treatments.

Area of Science:

  • Neurology
  • Neuroscience
  • Geriatrics

Context:

  • The understanding of vascular dementia has significantly advanced since its initial description.
  • Current research focuses on refining diagnostic criteria and understanding the complex nature of these disorders.

Purpose:

  • To provide a comprehensive review of vascular dementias.
  • To discuss the evolution of diagnostic criteria and the proposed broader definition of vascular cognitive disorders.
  • To explore the relationship between vascular cognitive impairment and Alzheimer's disease.

Summary:

  • This review examines the evolution of vascular dementia, including diagnostic criteria, natural history, neuroradiological findings, epidemiology, and its connection to Alzheimer's disease.
  • It highlights the proposed shift towards a broader classification of vascular cognitive disorders, encompassing vascular cognitive impairment in non-demented individuals.

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  • Current treatment strategies are also briefly discussed.

    • Impact:

    • This work offers a consolidated overview of vascular cognitive disorders, aiding clinicians and researchers in diagnosis and management.
    • It emphasizes the expanding scope of vascular cognitive impairment, necessitating updated diagnostic and therapeutic approaches.
    • Understanding the links with Alzheimer's disease may pave the way for novel therapeutic targets.