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Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

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Published on: March 15, 2024

Plexiforme neurofibroma with compromising of the penile function.

Rodrigo Barros¹, Andre G Cavalcanti, Luciano A Favorito

¹Division of Urology, Souza Aguiar Municipal Hospital, Rio de Janeiro, Brazil.

|March 18, 2008

Summary

This case study details a 26-year-old male with Von Recklinghausen's disease experiencing a penile mass. Surgical resection of the plexiform neurofibroma resolved the issue, preserving sexual function.

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An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

Area of Science:

Urology
Oncology
Genetics

Background:

Von Recklinghausen's disease, also known as neurofibromatosis type 1 (NF1), is a genetic disorder.
Neurofibromas are benign tumors that grow on nerve sheaths.
Plexiform neurofibromas are a complex type of neurofibroma that can affect various body parts, including the penis.

Observation:

A 26-year-old male presented with a penile mass causing sexual dysfunction.
Clinical examination revealed café au lait spots, subcutaneous neurofibromas, and Lisch nodules, indicative of NF1.
The penile mass was identified as a plexiform neurofibroma.

Findings:

Surgical resection of the penile plexiform neurofibroma was performed via subcoronal incision.
Pathological examination confirmed the diagnosis of plexiform neurofibroma.
The patient experienced a successful recovery with preserved penile sensation and erectile function.

Implications:

Surgical excision of penile plexiform neurofibromas is a viable treatment option for patients with NF1.
This approach can effectively restore sexual function compromised by penile masses.
Early diagnosis and intervention are crucial for managing NF1-related penile complications.