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Updated: Jul 6, 2026

Synthesis and Assay of Vibrio Quorum Sensing Inhibitors
Published on: May 31, 2024
Investigating biological activity spectrum for novel quinoline analogues 2: hydroxyquinolinecarboxamides with
Robert Musiol1, Dominik Tabak, Halina Niedbala
1Institute of Chemistry, University of Silesia, Szkolna 9, 40006 Katowice, Poland.
Abstract:
Two series of amides based on quinoline scaffold were designed and synthesized in search of photosynthesis inhibitors. The compounds were tested for their photosynthesis-inhibiting activity against Spinacia oleracea L. and Chlorella vulgaris Beij. The compounds lipophilicity was determined by the RP-HPLC method. Several compounds showed biological activity similar or even higher than that of the standard (DCMU). The structure-activity relationships are discussed.
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