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Updated: Jul 6, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

MDCT of the myocardium: a new contribution to ischemic heart disease

Alexis Jacquier1, Didier Revel, Maythem Saeed

  • 1Department of Radiology, Hopital de la Timone, University of Marseille Méditerranée, 264 rue St Pierre, 13385 Marseille Cedex 5, France. alexis.jacquier@ap-hm.fr <alexis.jacquier@ap-hm.fr>

Academic Radiology
|March 18, 2008
PubMed

Insights

Multidetector row computed tomography (MDCT) assesses myocardial injury by visualizing late enhancement, similar to MRI. This technology aids in diagnosing ischemic heart disease, a leading cause of death.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Diagnostic Technology

Background:

  • Cardiovascular diseases are a leading global cause of mortality.
  • Multidetector row computed tomography (MDCT) offers insights into coronary artery anatomy and left ventricular function.
  • Early research in the 1970s demonstrated CT's ability to visualize myocardial infarction in animal models.

Purpose of the Study:

  • To review the technical aspects of cardiac MDCT for myocardial assessment.
  • To explore the diagnostic potential of MDCT in ischemic heart disease.

Main Methods:

  • Utilizing multidetector row computed tomography (MDCT) for cardiac imaging.
  • Assessing myocardial late enhancement, analogous to delayed enhancement MRI.
  • Evaluating coronary artery anatomy and left ventricular volume and function.

Main Results:

  • MDCT technology has enabled clinical application of CT for myocardial assessment.
  • MDCT can visualize myocardial injury in both animal models and human patients.
  • The principle of MDCT assessment of myocardial late enhancement mirrors that of delayed enhancement MRI.

Conclusions:

  • Cardiac MDCT is a valuable tool for assessing the myocardium.
  • MDCT holds significant potential for diagnosing ischemic heart disease.
  • Advancements in MDCT have revived and expanded the clinical utility of CT for cardiac evaluation.
Abstract

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