The Influence of Affect on Cognition
The Influence of Cognition on Affect
Depressive Disorders: Etiology
Depression: Overview
Depressive Disorders: MDD and Dysthymia
First Impression
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Updated: Jul 6, 2026

An Olfactory Preference Test for Measuring Olfactory Hedonic Biases in Mouse Models of Depression
Published on: July 11, 2025
Jackie K Gollan1, Heather T Pane, Michael S McCloskey
1Department of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, 446 East Ontario Street, Suite 7-204, Chicago, IL 60611, USA. j-gollan@northwestern.edu
Major depression is linked to slower processing of sad facial expressions and a bias toward interpreting neutral faces as sad. Healthy individuals are more likely to perceive neutral faces as happy.
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