Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A joint model for longitudinal measurements and survival data in the presence of multiple failure types.

Biometrics·2007
Same author

Na+-dependent neutral amino acid transporter ASCT2 is downregulated in seriously traumatized human intestinal epithelial cells.

Journal of pediatric gastroenterology and nutrition·2007
Same author

The health effects of non-industrial indoor air pollution.

The Journal of allergy and clinical immunology·2007
Same author

Biodiversity of pig breeds from China and Europe estimated from pooled DNA samples: differences in microsatellite variation between two areas of domestication.

Genetics, selection, evolution : GSE·2007
Same author

Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription.

Genome research·2007
Same author

Functional roles of a Ca2+-activated K+ channel in atrioventricular nodes.

Circulation research·2007
Same journal

Integrating transcriptomics and metabolomics reveals the molecular landscape of sperm maturation driven by regional differentiation in the epididymis of Guizhou-Guiqian semi-fine wool sheep.

Genomics·2026
Same journal

Impact of genotype on histopathology and clinical characters in a Chinese cohort with obstructive hypertrophic cardiomyopathy.

Genomics·2026
Same journal

A novel reusable transcriptome-wide association study workflow used to map key genes linked to important cattle traits.

Genomics·2026
Same journal

The large mitochondrial genome of Syndiclis anlungensis (Lauraceae): Genome structure, comparative analysis, and phylogenetic relationships with other Syndiclis species.

Genomics·2026
Same journal

DeepGEP: Deep learning for gene expression prediction from multi-omics in mammals.

Genomics·2026
Same journal

Molecular features of external Auditory Canal cholesteatoma by microbial metagenomic sequencing.

Genomics·2026
See all related articles

Related Experiment Video

Updated: Jul 6, 2026

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis
12:29

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis

Published on: April 16, 2018

DHPC: a new tool to express genome structural features.

Xuegong Deng1, Xuemei Deng, Simon Rayner

  • 1State Key Laboratory of Agrobiotechnology and Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, China Agricultural University, Beijing 100094, China.

Genomics
|March 18, 2008
PubMed
Summary
This summary is machine-generated.

The DNA Hilbert-Peano curve (DHPC) visualizes genomes as 2D images, revealing sequence features like base composition and repeats. This method aids in identifying previously unknown genomic characteristics.

More Related Videos

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

Related Experiment Videos

Last Updated: Jul 6, 2026

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis
12:29

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis

Published on: April 16, 2018

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Visualizing large-scale genome sequences is challenging.
  • Existing methods may not effectively reveal complex genomic characteristics.

Purpose of the Study:

  • Introduce the DNA Hilbert-Peano curve (DHPC) as a novel visualization tool.
  • Demonstrate DHPC's capability in identifying genomic features.

Main Methods:

  • Mapping genome sequences into a 2D square using Hilbert-Peano space-filling curves.
  • Applying Gauss smoothing and user-defined color functions for image generation.
  • Analyzing calculated DHPCs for genomic characteristics.

Main Results:

  • DHPCs reveal genome characteristics such as base composition, repeating sequences, and homogeneity regions.
  • The method effectively identifies boundaries of homogeneous regions and annotated segments.
  • DHPC visualization highlighted previously unidentified sequence features in analyzed genomes.

Conclusions:

  • DHPC is an effective tool for visualizing and analyzing large-scale genome sequences.
  • The method aids in the discovery of novel genomic features and sequence patterns.
  • DHPC offers a powerful approach for exploring genome complexity.