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Related Concept Videos

Human Virome01:26

Human Virome

The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible only with...
Bacteriophages of the Human Virome01:23

Bacteriophages of the Human Virome

Bacteriophages are found throughout the human body. They may even outnumber eukaryotic viruses, forming an important and dynamic component of the human virome. Indeed, phages represent the most abundant viral entities, with densities in the gut reaching up to 10⁹ particles per gram of fecal matter, and many belonging to orders such as Caudovirales and Microviridae, while a substantial proportion remains unclassified as viral “dark matter.”Lysogeny and Genetic ExchangeIn the gut, bacteriophages...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

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[Bocavirus: a new human parvovirus].

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[Human polyomaviruses recently identified in humans].

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[Human bocavirus (HBoV): from discovery through molecular screening to observation by electron microscopy].

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Related Experiment Video

Updated: Jul 6, 2026

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses
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Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses

Published on: November 24, 2014

[Human bocavirus (HBoV)].

V Foulongne1, M Segondy

  • 1Unité de virologie, pôle d'infectiologie, CHU de Montpellier-St-Eloi, 80, avenue A.-Fliche, 34295 Montpellier cedex 5, France. v-foulongne@chu-montpellier.fr

Pathologie-Biologie
|March 18, 2008
PubMed
Summary

Human bocavirus (HBoV) is a common cause of respiratory illness in children worldwide. Viral load measurement may help distinguish infection from carriage.

Area of Science:

  • Virology
  • Molecular Biology
  • Epidemiology

Context:

  • Human bocavirus (HBoV), a Parvoviridae family member, is increasingly identified in pediatric respiratory infections.
  • Prevalence ranges from 5-10% globally, primarily affecting children during winter months.
  • Near-universal seroprevalence in children by age five suggests limited adult susceptibility.

Purpose:

  • To summarize the current understanding of human bocavirus (HBoV) in pediatric respiratory disease.
  • To highlight diagnostic approaches and potential clinical applications.

Summary:

  • HBoV is detected in respiratory secretions of children with acute respiratory illness using molecular methods like PCR.
  • Co-detection with other respiratory viruses is common; its role in gastroenteritis remains unclear.

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Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
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Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

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Related Experiment Videos

Last Updated: Jul 6, 2026

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses
06:13

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses

Published on: November 24, 2014

Titration of Human Coronaviruses Using an Immunoperoxidase Assay
12:00

Titration of Human Coronaviruses Using an Immunoperoxidase Assay

Published on: April 28, 2008

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

Published on: September 22, 2023

  • Quantifying viral DNA load in respiratory secretions may differentiate symptomatic HBoV infection from asymptomatic carriage.

    • Impact:

    • Establishes HBoV as a significant pediatric respiratory pathogen.
    • Suggests viral load quantification as a potential diagnostic tool for HBoV infections.
    • Informs clinical management and public health strategies for respiratory viral infections in children.