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Myelopathy but normal MRI: where next?

S H Wong¹, M Boggild, T P Enevoldson

¹The Walton Centre for Neurologyand Neurosurgery NHS Trust,Fazakerley, Liverpool, UK. Sui.Wong@thewaltoncentre.nhs.uk

Practical Neurology

|March 18, 2008

Summary

This summary is machine-generated.

Neurologists often face "MRI normal myelopathy," a diagnostic challenge where spinal cord syndrome symptoms appear without clear MRI findings. This review explores differential diagnoses and further investigations for this complex neurological condition.

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Area of Science:

Neurology
Radiology
Diagnostic Imaging

Background:

Magnetic resonance (MR) scanning is the primary diagnostic tool for spinal cord syndromes.
Myelopathy, or spinal cord dysfunction, can present with normal spinal imaging, posing a diagnostic challenge.

Observation:

Patients may exhibit clinical signs of myelopathy despite unremarkable spinal MR imaging results.
This scenario, termed "MRI normal myelopathy," requires careful consideration of alternative diagnoses.

Findings:

This review discusses key differential diagnoses for neurologists encountering "MRI normal myelopathy."
Case examples illustrate the diagnostic process and highlight potential investigations.

Implications:

Accurate diagnosis of myelopathy with normal imaging is crucial for appropriate patient management.
Further investigation strategies are essential for identifying the underlying cause of neurological deficits.