Related Experiment Video
Updated: Jul 6, 2026
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Comparison between staple and vessel sealing device for parynchemal transection in laparoscopic liver surgery in a
Reza F Saidi1, Ahmad Ahad, Rossini Escobar
1Department of Surgery, Providence Hospital and Medical Centers, Southfield, MI, USA.
Background:
Advancements in technology have allowed laparoscopic surgery to expand into advanced procedures such as liver resection; however, the transection method is debatable. This study was designed to evaluate the feasibility and outcome of laparoscopic liver resection comparing the vessel sealing device (VSD) versus endomechanical stapling devices for parenchymal transection in a swine model.
Materials And Methods:
Laparoscopic left hepatectomy was performed in two groups (n=7 in each group) comparing the stapler device with the VSD. The cut surfaces of the liver were evaluated for bleeding and biliary leakage at the time of the operation and 1 week later. The animals were sacrificed 1 week after the operation to determine hemorrhage and bile leakage, and to allow histological evaluation of the liver. Serum liver enzymes were checked before, after, and 1 week postoperatively.
Results:
No evidence of biliary leakage or hemorrhage was noted at the time of the operation and 1 week later for both groups. There was a trend toward an increase in blood loss in the stapled group compared with LigaSure (40+/-16.4 cc vs 17+/-3.7 cc, p>0.05). There was also a trend toward shorter transection time in the stapled group compared with the LigaSure group (15+/-4.1 min vs 21.8+/-5.3, p>0.05). The instrument cost was significantly higher in the stapled group (720+/-110 vs 400+/-50; p<0.05). There was no difference in serial liver enzymes and liver histopathology in the two groups.
Conclusions:
The VSD and endomechanical stapler can be safely and effectively used for parenchymal transection during laparoscopic liver resection. However, using endomechanical staplers is associated with an increase in cost.
