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[Diabetes insipidus in a pacient with multiple sclerosis]
Fernanda G Weiler1, Kátia Blumberg, Claudia S Liboni
1Disciplina de Medicina de Urgência, Universidade Federal de São Paulo, Brazil. fegweiler@yahoo.com.br
Arquivos Brasileiros De Endocrinologia E Metabologia
|March 18, 2008
Summary
Multiple Sclerosis (MS) can cause central diabetes insipidus (DI), a rare condition characterized by excessive thirst and urination. Early recognition and desmopressin treatment can effectively manage these symptoms in MS patients.
Area of Science:
- Neurology
- Endocrinology
Background:
- Multiple Sclerosis (MS) is a chronic demyelinating disease affecting the central nervous system.
- Central diabetes insipidus (DI) results from damage to the hypothalamus or pituitary stalk.
- MS is a potential, though infrequently described, cause of central DI.
Observation:
- Clinical suspicion of central DI in MS patients arises with polyuria, polydipsia, or unexplained hypernatremia.
- This report details a case of MS-associated central DI.
Findings:
- The patient presented with symptoms consistent with central DI during the course of MS.
- Desmopressin therapy was initiated for the management of DI.
Implications:
- This case highlights the importance of considering central DI in the differential diagnosis of MS patients with polyuria/polydipsia.
- Timely diagnosis and desmopressin treatment can reverse DI symptoms in the context of MS.
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