Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinician treatment choices for post-traumatic stress disorder: ambassadors survey of psychiatrists in 39 European countries.

European psychiatry : the journal of the Association of European Psychiatrists·2024
Same author

Clinical decision-making style preferences of European psychiatrists: Results from the Ambassadors survey in 38 countries.

European psychiatry : the journal of the Association of European Psychiatrists·2022
Same author

Understanding Barriers to the Realization of Human Rights Among Older Women With Mental Health Conditions.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2021
Same author

COVID-19 and dementia: experience from six European countries.

International journal of geriatric psychiatry·2021
Same author

Pathways to care for people with dementia: An international multicentre study.

International journal of geriatric psychiatry·2019
Same author

Development of an international schedule for the assessment and staging of care for dementia.

Journal of Alzheimer's disease : JAD·2014

Related Experiment Video

Updated: Jul 6, 2026

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

[Depression in old age].

Gabriela Stoppe1

  • 1Universitäre Psychiatrische Kliniken, Wilheml Klein-Strasse 27, Basel, Switzerland. gabriela.stoppe@upkbs.ch

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
|March 18, 2008
PubMed
Summary
This summary is machine-generated.

Depression is common in older adults, presenting with physical and cognitive issues. Improved recognition and integrated treatments, including psychotherapy, are crucial for this growing population.

More Related Videos

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Related Experiment Videos

Last Updated: Jul 6, 2026

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

  • Geriatrics
  • Psychiatry
  • Public Health

Background:

  • Depression is the most common psychiatric disorder in the elderly, often presenting with somatic or cognitive complaints.
  • Older adults with depression experience a worse prognosis for comorbid physical conditions and have a high suicide rate.
  • Depression is a risk factor for dementia and institutionalization, with complex interactions with organic brain disorders.

Purpose of the Study:

  • To highlight the challenges of depression in old age.
  • To emphasize the need for increased recognition and treatment rates.
  • To advocate for the development of integrative treatment plans and increased psychotherapy.

Main Methods:

  • Review of existing literature on geriatric depression.
  • Analysis of risk factors, consequences, and treatment approaches.
  • Discussion of the interplay between depression, dementia, and other organic brain disorders.

Main Results:

  • Older adults exhibit distinct depressive symptoms and risk factors, including physical and sleep disorders, and loss of spouse.
  • Depression negatively impacts comorbid somatic disorders and increases suicide risk.
  • Current treatment practices are often inadequate, with drug therapies dominating over psychotherapy.

Conclusions:

  • Geriatric depression poses a significant challenge to healthcare systems due to low recognition and treatment rates.
  • Integrative treatment plans addressing comorbid physical disorders are needed.
  • Evidence for effective treatments must be increased, promoting psychotherapy and specialized geriatric psychotherapists.