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Chronic daily headache

Giuseppe Nappi1, Armando Perrotta, Paolo Rossi

  • 1University Centre for Adaptive Disorders and Headache, IRCCS C. Mondino Institute of Neurology Foundation, University of Pavia, Italy. giuseppe.nappi@mondino.it

Expert Review of Neurotherapeutics
|March 19, 2008
PubMed

Insights

Chronic daily headache (CDH) affects millions globally, encompassing various headache types, often evolving from episodic forms. This review covers CDH classification, causes, and treatment options.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Chronic daily headache (CDH) is a prevalent condition affecting 4-5% of the global population.
  • It encompasses a heterogeneous group of headaches, including transformed migraine and chronic tension-type headache, often linked to medication overuse.

Purpose of the Study:

  • To review the classification, pathophysiology, and therapeutic approaches for chronic daily headaches.
  • To address the ongoing debate in CDH classification and the lack of approved specific therapies.

Main Methods:

  • Literature review of existing studies on CDH.
  • Analysis of classification criteria and diagnostic challenges.
  • Overview of current pharmacological and non-pharmacological treatment strategies.

Main Results:

  • CDH presents diagnostic challenges, though recent criteria revisions have improved classification.
  • Few large-scale controlled trials exist for CDH treatments.
  • The review synthesizes current knowledge on CDH pathophysiology and therapeutic options.

Conclusions:

  • Effective management of CDH requires addressing classification ambiguities and advancing therapeutic research.
  • A comprehensive understanding of CDH pathophysiology is crucial for developing targeted treatments.

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