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[Perifollicular xanthomatosis as a key histological finding in Fox-Fordyce disease]
J Mataix1, J F Silvestre, M Niveiro
1Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, España. mataixdiaz@hotmail.com
Abstract:
Fox-Fordyce disease is a rare skin condition characterized by the presence of multiple pruritic follicular papules in areas rich in apocrine glands, such as the axillae, mammary areolae, or genital regions. There is a high degree of variability in the histological findings seen in Fox-Fordyce disease. In addition to those described as typical of this entity, such as dilation of the infundibulum and hyperkeratosis and spongiosis of the infundibular epithelium, many other histological changes can be observed. We report the case of a 21-year-old woman with Fox-Fordyce disease and highlight the importance of perifollicular xanthomatosis as a key histological finding in the diagnosis of the disease.
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