Does abnormal bile acid metabolism contribute to NEC?

Melissa D Halpern1, Bohuslav Dvorak

  • 1Department of Pediatrics, University of Arizona, Tucson, AZ 85724-5073, USA. mhalpern@peds.arizona.edu

Summary

Bile acids (BAs) accumulate in the intestine during necrotizing enterocolitis (NEC), worsening the condition. Preventing BA accumulation reduces NEC severity, suggesting a key role for bile acids in this disease.

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