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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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Related Experiment Videos

Synovial sarcoma: a case report.

Albert V Armstrong1, Andrea Aedo, Sarah Phelps

  • 1Division of Medicine, School of Podiatric Medicine, Barry University, Miami Shores, FL 33161, USA. aarmstrong@mail.barry.edu

Clinics in Podiatric Medicine and Surgery
|March 19, 2008
PubMed
Summary

Synovial sarcoma, a common foot cancer in adults, presents as soft tissue swelling. Early imaging is crucial for diagnosis and understanding its potential spread.

Area of Science:

  • Orthopedic Oncology
  • Radiology
  • Soft Tissue Pathology

Background:

  • Synovial sarcoma is a prevalent soft tissue sarcoma, typically affecting adults aged 30-50.
  • It frequently occurs in the foot, often near bone structures.
  • Encapsulated tumors can invade surrounding nerves and vasculature due to limited anatomical barriers.

Observation:

  • A case study of a young patient presenting with right foot soft tissue swelling is detailed.
  • The diagnostic imaging protocol for suspected foot sarcomas is outlined.
  • The clinical presentation and diagnostic challenges of synovial sarcoma are highlighted.

Findings:

  • Synovial sarcoma exhibits characteristic imaging findings that aid in diagnosis.
  • Early detection is critical due to the potential for rapid malignant spread.

Related Experiment Videos

  • The literature review provides comprehensive insights into synovial sarcoma epidemiology and behavior.
  • Implications:

    • This case underscores the importance of thorough imaging protocols for foot swelling.
    • Understanding tumor biology aids in predicting and managing metastatic potential.
    • Enhanced diagnostic strategies can improve patient outcomes for synovial sarcoma.