Injectable botulinum toxin as a treatment for plantar hyperhidrosis: a case study

Area of Science:

• Dermatology
• Neurology

Background:

• Hyperhidrosis involves excessive sweating from overactive eccrine glands.
• Plantar hyperhidrosis (foot sweating) is typically managed with topical solutions and iontophoresis.
• Limited, poorly tolerated options exist for treatment-resistant cases.

Observation:

• Botulinum toxin type A is FDA-approved for severe axillary hyperhidrosis.
• Recent studies suggest efficacy for plantar hyperhidrosis.
• This case study involved intradermal injections of botulinum toxin type A into the feet of two patients.

Findings:

• Botulinum toxin type A injections were administered to the plantar aspect of both feet.
• A 3-month follow-up assessed residual sweating subjectively.
• The treatment demonstrated effectiveness and safety for plantar hyperhidrosis in both patients.

Implications:

• Botulinum toxin type A represents a viable and safe therapeutic option for recalcitrant plantar hyperhidrosis.
• Further research may validate its use in a broader patient population.
• This approach could improve quality of life for individuals with severe foot sweating.