Related Experiment Video
Updated: Jul 6, 2026
09:56
In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Choroidal neovascularization in pathologic myopia: recent developments in diagnosis and treatment
1Clinique Ophtalmologique Universitaire de Créteil, Paris XII-Val-de-Marne, France.
Survey of Ophthalmology
|March 20, 2008
Summary
Pathologic myopia can cause choroidal neovascularization, leading to vision loss and career impact. This review evaluates current and emerging treatments for this condition.
Area of Science:
- Ophthalmology
- Medical Research
Background:
- Pathologic myopia frequently causes choroidal neovascularization (CNV), a leading cause of irreversible vision loss.
- CNV significantly impacts individuals of working age, affecting career prospects and financial stability.
- Recent advancements offer new hope for managing this vision-threatening complication.
Purpose of the Study:
- To review the epidemiology, risk factors, and pathology of CNV secondary to pathologic myopia.
- To evaluate current and emerging treatment options for CNV in pathologic myopia.
- To provide an evidence-based assessment of therapeutic interventions.
Main Methods:
- Literature review of epidemiology, risk factors, and pathology.
- Evaluation of clinical features and diagnostic methods.
- Assessment of evidence for treatment modalities including laser photocoagulation, photodynamic therapy, and surgery.
Main Results:
- Pathologic myopia is a significant risk factor for CNV.
- Treatment options for CNV have historically been limited but are expanding.
- Evidence supports the efficacy of various interventions, with ongoing research.
Conclusions:
- CNV in pathologic myopia presents a substantial challenge to vision and quality of life.
- A comprehensive understanding of treatment efficacy is crucial for patient management.
- Further research is needed to optimize therapeutic strategies.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...