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Published on: December 1, 2023
Interoperability of GADU in using heterogeneous grid resources for bioinformatics applications
Dinanath Sulakhe1, Alex Rodriguez, Michael Wilde
1Computation Institute, University of Chicago, Chicago, IL 60637, USA. sulakhe@mcs.anl.gov
Summary
Genome analysis requires significant computing power. The Genome Analysis and Database Update system (GADU) automates access to grid resources, enabling efficient bioinformatics analysis across diverse platforms.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
Background:
- High-throughput bioinformatics tools demand substantial computational resources for genetic sequence analysis.
- Grid computing resources like Open Science Grid and TeraGrid offer scalable solutions for scientific discovery.
Purpose of the Study:
- To describe the requirements for an automated, scalable system (GADU) for running bioinformatics applications on diverse Grid resources.
- To present the architecture of GADU, emphasizing its resource independence and interoperability.
Main Methods:
- Development of the Genome Analysis and Database Update system (GADU).
- Implementation of a resource-independent configuration using the Pegasus-based virtual data system.
- Focus on automating access to heterogeneous Grid resources for bioinformatics tasks.
Main Results:
- GADU enables automated, high-throughput execution of bioinformatics applications on various Grid infrastructures.
- The system's resource-independent design ensures interoperability across heterogeneous Grid environments.
- GADU acts as a gateway for computationally intensive bioinformatics applications on the Grid.
Conclusions:
- GADU provides an automated and scalable solution for large-scale bioinformatics analyses on distributed Grid resources.
- The system's architecture facilitates interoperability and efficient utilization of heterogeneous Grid computing environments.
- GADU enhances the accessibility and throughput of complex bioinformatics applications in a Grid setting.
