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Updated: Jul 6, 2026

Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)
Published on: March 24, 2016
Sealed-cell mercury resonance ionization imaging detector
Abstract:
A sealed, compact mercury atomic-absorption resonance ionization imaging detector has been developed and evaluated. The sensitivity of the detector as well as its ability to form two-dimensional images has been demonstrated. Images of faint light (1000 photons) have been recorded by image summation. It is shown that one can obtain high-quality images with a spatial resolution of at least 130 mum by detecting the ionic component of the imaging signal. Distortion, more noise, and poorer spatial resolution were observed when the electron component of the signal was detected. We studied the influence of voltage on the cell electrodes to find the conditions for optimum signal-to-noise ratio.
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