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Updated: Jul 6, 2026
03:37
Intravitreal Injections in the Ovine Eye
Published on: July 5, 2022
[Intravitreal injections during anticoagulant treatment]
Klinische Monatsblatter Fur Augenheilkunde
|March 21, 2008
Summary
Intravitreal injections are safe for patients on oral anticoagulation or antiplatelet therapy. This study found no significant increase in bleeding complications, allowing continued medication during eye injections.
Area of Science:
- Ophthalmology
- Vascular Medicine
Background:
- Intravitreal injections are increasingly common procedures.
- Patient safety during these injections, particularly for those on anticoagulant or antiplatelet medications, requires careful evaluation.
Purpose of the Study:
- To prospectively assess the safety of intravitreal injections in patients concurrently receiving oral anticoagulation or antiplatelet therapy.
- To determine the incidence of intra- or extraocular hemorrhages post-injection in this patient cohort.
Main Methods:
- Prospective study involving 57 patients undergoing 80 intravitreal injections (Ranibizumab, Bevacizumab, or triamcinolone).
- Documentation of post-injection intra- or extraocular hemorrhages.
- Comparison of outcomes between patients on oral anticoagulation versus antiplatelet therapy.
Main Results:
- Small subconjunctival hemorrhages observed in 45% of eyes.
- No instances of subtotal subconjunctival or vitreous hemorrhage occurred.
- No significant difference in bleeding complications was noted between patients on oral anticoagulation and those on antiplatelet therapy.
Conclusions:
- Intravitreal injections can be safely administered without the need to discontinue oral anticoagulation or antiplatelet therapy.
- This finding supports current clinical practice and may reduce patient management complexity.
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