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Src kinase induces tumor formation in the c-SRC C57BL/6 mouse

Christina Leah B Kline1, Rosalind Jackson, Robert Engelman

  • 1Penn State Cancer Institute H072, Penn State College of Medicine, 500 University Drive, PO 850, Hershey, PA 17033, USA.

International Journal of Cancer
|March 21, 2008
PubMed
Summary

Src kinase, elevated in cancers like colon and breast, may drive tumor development. This study used transgenic mice to show that high Src expression alone can cause liver tumors, suggesting its role in carcinogenesis.

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