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Updated: Jul 6, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
Published on: August 31, 2021
Force between colloidal particles in a nematic liquid crystal studied by optical tweezers
Kenji Takahashi1, Masatoshi Ichikawa, Yasuyuki Kimura
1Department of Physics, School of Sciences, Kyushu University, Fukuoka, Japan. ken8scp@mbox.nc.kyushu-u.ac.jp
Abstract:
We measure the dependence of the interparticle force F on the distance R between two colloidal particles with hyperbolic hedgehog defects in a nematic liquid crystal using optical tweezers. The particle-defect pair can be regarded as an elastic "dipole" in the electrostatic analogy. In a parallel configuration, where the dipole vectors are parallel with each other, F is attractive and proportional to R(-4). However, F becomes repulsive at small R due to the existence of a defect between the particles. In an antiparallel configuration, where the particles directly face each other, F is repulsive over the whole range of R and proportional to R(-3.6). In another antiparallel configuration, where two hyperbolic hedgehog defects directly face each other, F is proportional to R(-3.6) and F at small R turns out to be attractive upon tilting the dipoles. Furthermore, we yield the force between particles connected by a stringlike defect called a bubblegum defect.

