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Related Experiment Videos

Urinary retention associated with ipratropium bromide.

E Pras1, S Stienlauf, J Pinkhas

  • 1Department of Medicine D, Beilinson Medical Center, Petah Tiqva, Israel.

DICP : the Annals of Pharmacotherapy
|September 1, 1991
PubMed
Summary

Nebulized ipratropium bromide can cause urinary retention, a rare side effect. Elderly men with prostate hypertrophy should use this medication cautiously due to this risk.

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Area of Science:

  • Pulmonology
  • Geriatrics
  • Pharmacology

Background:

  • Chronic obstructive lung disease (COPD) exacerbations require effective management.
  • Anticholinergic bronchodilators like ipratropium bromide are commonly used in COPD treatment.

Observation:

  • A 69-year-old male patient experienced acute urinary retention during treatment for a COPD exacerbation.
  • The urinary retention resolved spontaneously after discontinuation of nebulized ipratropium bromide.

Findings:

  • Urinary retention is identified as a rare adverse event associated with ipratropium bromide therapy.
  • The existing literature indicates a predisposition for this complication in elderly males with pre-existing benign prostatic hyperplasia (BPH).

Implications:

  • Clinicians should exercise caution when prescribing ipratropium bromide to elderly male patients, particularly those with BPH.
  • Awareness of this potential side effect is crucial for timely diagnosis and management in at-risk populations.
  • Further investigation into the mechanisms underlying ipratropium-induced urinary retention in this demographic may be warranted.

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