Related Experiment Video
Updated: Jul 6, 2026
03:42
Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
Published on: March 15, 2024
Complicated acute appendicitis in diabetic patients.
Shih-Hung Tsai1, Chin-Wang Hsu, Shin-Chieh Chen
1Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Cheng-Kung Rd., Sec. 2, Neihu 114, Taipei, Taiwan.
American Journal of Surgery
|March 21, 2008
Summary
Diabetic patients face a higher risk of complicated appendicitis and longer hospital stays. Delayed diagnosis, particularly in those with diabetic nephropathy and impaired renal function, significantly increases this risk.
Area of Science:
- Gastroenterology
- Endocrinology
- Surgical Outcomes
Background:
- Diabetes mellitus (DM) is linked to adverse outcomes in gastrointestinal diseases.
- Investigating the increased risk of complicated acute appendicitis (CAA) in diabetic patients is crucial.
Purpose of the Study:
- To determine if diabetic patients have a higher risk of developing complicated acute appendicitis (CAA) compared to non-diabetic individuals.
- To identify risk factors associated with CAA in diabetic patients.
Main Methods:
- A retrospective study analyzed 1,184 patients diagnosed with acute appendicitis over five years.
- Diabetic and non-diabetic patient groups were compared for the incidence of CAA and hospital stay duration.
Main Results:
- Diabetic patients (71/1184) exhibited a higher risk of CAA and prolonged hospitalization.
- DM was identified as an independent risk factor for CAA, even after adjusting for age and sex.
- Delayed diagnosis, diabetic nephropathy history, and poorer renal function were associated with CAA in diabetic patients.
Conclusions:
- Diabetic patients have an elevated risk of developing CAA, leading to longer hospital stays.
- Delayed diagnosis, indicated by longer symptom-to-diagnosis duration, is the primary risk factor for CAA in diabetics.
- Diabetic nephropathy and impaired renal function also contribute to CAA development.
Related Concept Videos
01:19Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
01:29Appendicitis-II: Diagnostic Studies and Management
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
01:22Complications of Diabetes Mellitus
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
01:22Appendicitis-I: Introduction
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
01:30Acute Pancreatitis II: Clinical Manifestations and Management
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
01:31Diabetic Foot Ulcer
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...