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Published on: June 6, 2025
Control of hypertension in coronary heart disease
Insights
Out-of-office blood pressure control in coronary heart disease (CHD) patients is significantly better than in-office readings. Ambulatory blood pressure monitoring (ABPM) reveals higher hypertension control rates, offering a more accurate patient assessment.
Area of Science:
- Cardiology
- Hypertension Research
- Preventive Medicine
Background:
- Investigates out-of-office hypertension control in coronary heart disease (CHD) patients using 24-h ambulatory blood pressure monitoring (ABPM).
- Utilizes data from the Spanish Society of Hypertension ABPM Registry, encompassing a large network of primary care physicians.
- Compares out-of-office BP control with traditional in-office measurements in treated essential hypertensive patients with CHD.
Discussion:
- Out-of-office hypertension control (46.4%) significantly exceeded in-office control (28.7%) in 2434 treated CHD patients.
- Identified 'office resistance' in 25.2% of patients, characterized by normal ambulatory BP but elevated office BP despite treatment.
- Highlights the discrepancy between office and ambulatory BP measurements in assessing hypertension control.
Key Insights:
- Ambulatory blood pressure monitoring (ABPM) provides a more accurate assessment of hypertension control in CHD patients compared to office BP.
- A substantial proportion of patients exhibit 'office resistance,' masking true BP control status.
- Current hypertension management strategies may overestimate control based solely on office readings.
Outlook:
- Further efforts are required to optimize BP control in CHD patients.
- Physicians can be reassured by potentially better BP control than previously estimated from office data.
- Recommends the integration of ABPM for a more comprehensive understanding of hypertension management in CHD.
Abstract:
This observational study investigates, for the first time, the actual or out-of-office control of hypertension among coronary heart disease (CHD) patients, by using 24-h ambulatory BP monitoring (ABPM). We used the Spanish Society of Hypertension ABPM Registry, based on a large-scale network of primary-care physicians consecutively recruiting hypertensive patients with conventional clinical indications for ABPM. The average of two office BP measurements was used for analyses. Thereafter, 24-h ABPM was performed, using a SpaceLabs 90207 device. Out-of-office control of hypertension among 2434 treated essential hypertensive patients with clinically documented CHD was much higher (46.4%) than in-office BP control (28.7%). This considerable difference was partly due to the presence of 25.2% of patients with "office resistance", i.e., normal ambulatory BP but with high office BP despite treatment. Although further efforts in controlling BP are needed in CHD patients, physicians should be also comforted by BP results better than previously believed based on office data.
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